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KMID : 0359319910310040425
Korean Journal of Veterinary Research
1991 Volume.31 No. 4 p.425 ~ p.431
Studies on the safety of recombinant bovine somatotropin in dairy cow


Abstract
Effects of recombinant bovine somatotropin(¥ãBST) on mineral composition of milk were investigated in Twenty-five multiparous Holstein dairy cows. Recombinant BST was administered by two different routes; intramusculary(12.5§· and 25§·/day) and subcutaneously (500§· and 750§·) in sustained-release vehicle every 2 weeks beginning 4 week postpartum and continuing for 7 months.
Milks were collected 0,1, 2, 3, 5 and 7 months after beginning of treatments in control and rBST-administered groups.
Mineral composition, such as Ca, Pi, Na, K, Mg, Zn, Fe and Mn, in milk were not affected by the administration of ¥ãBST regardless of dose and dosage forms.
It is concluded from the observations of these experiments that the dose and dosage forms of ¥ãBST employed in this work might not affect milk mineral composition in dairy cows under the normal sanitary condition and adequate nutrient bulance.
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